We love these two compounds and the resulting effect that makes cannabis such a beneficial medicine.  But what exactly are CBD and THC and how do they work in the body? Our bodies have a set of receptors found in our endocannabinoid system that interacts with cannabis compounds called cannabinoids, like THC and CBD. Research has shown that using both CBD and THC together, especially when other cannabis compounds are present, create an “entourage effect” which can provide even more benefits than when taking THC or CBD alone. 

What is the Difference Between CBD & THC?

CBD (Cannabidiol)

CBD is a non-intoxicating cannabinoid that influences cannabinoid receptor activity and encourages production of the body’s natural endocannabinoids. It does not activate the same cannabinoid receptors as THC so it does not produce the euphoric, psychoactive effects of THC.

THC (Tetrahydrocannabinol)

THC is the compound responsible for creating the psychoactive effect. It attaches to cannabinoid receptors concentrated in certain areas of the brain associated with thinking, memory, pleasure, coordination and time perception. THC stimulates cells in the brain to release dopamine, creating the classic cannabis euphoria.

How do CBD & THC Work Together?

Medicine with both compounds will show a CBD:THC ratio. Which ratios work best will vary from person to person depending on how this combo is used and for what purpose. As mentioned above, the combination of the two cannabinoids with other cannabinoids and terpenes found in cannabis creates an “entourage effect.” When more than one cannabinoid is present, the benefits of each compound work together as a whole to create a fuller effect.

CBD can also mitigate the effects of THC! If you find yourself beyond your comfort level of euphoria, CBD can help even out or reduce your high, but the dosage is important. Studies have shown that a low dose of CBD (5mg) may actually increase your high. However, a higher dosage of CBD (50mg+) can be effective in reducing a euphoric high.